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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '912996a8198fb600624fe1129ce2ee87e17a18bfd2e9625fa2fbc1e0e304a379' 
  AND token = 'XI44Sd7ETp3TRrTNviFe+t9ztzaqm3B9mVBDFeBKz9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}