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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'addec9121abfa29e7d6f0fad59fa96b9d5de165f1dd9f8ae740829c52bf6c41c' 
  AND token = 'LukbGvf/OgTFvbF2F+xsNZi7BM22KJcEosZmtFytVWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}