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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e7b7eb5f13d3c884fb54f25c4c73372237b210c7976e62c30f5f2c221eb577' 
  AND token = 'OeRz6tLPmoI286j9JCr5QMJwU/1u/wLoJjIu21nY4Mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}