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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4e2d52cf493069fe1bd4ba2b09d254a1191b293d80fc67ba1d77a17d60fd9e1' 
  AND token = 'pIJAE8VXbYtwgFJEZUN4562XDY/mk/pBSFiKxFa8fRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}