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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246ea95eb48466ab6d1e721f0d536e2a3eecd8023ae6965231a673d6f79f2469' 
  AND token = 'OZWTv4ADxdoXrNaDZYjrbbpmOC++TiD09+FN8BJcJKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}