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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dffbb047462d90b641acf1fc017f8a112f58e7748a66016500667ec8ead1251' 
  AND token = '+jP+B2+Gfoer1VcimewF1fH2H9PopJlA+FQrkIN4MJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}