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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e994bd0660502ab612cc83b3512d51d86f62ec0c3ef821aafec50104c1d660c' 
  AND token = 'g220r3YNCyygTV1TYzUCRQGJtVHquwyOlsoHsediF5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}