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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dcffa784b845d741f03abcbe4f01a7c24587f2143536a7481370ec333ad4b33' 
  AND token = 'x9aTzCX4Zh1P0m9c3M07Deo/65JtO3U/Lf3qlsCEm4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}