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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8cf2ad12ab7669f17fb36b9fcdb557f1103392b0f1671d7560e0f42cee5424f' 
  AND token = 'GLir+fqQZewYklbs0kIdy6TwmL5cDrz4jO8iG0b91J4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}