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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ad781c08c14c42976b86563300daedc57116bccc886deb9d54a34ea06f07032' 
  AND token = 'j83vqUBSeUFt9Mct96dRNASh+tSNWqk+49G/HTC5Zak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}