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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '139a4deef930de4d3f3756dd1d94387562a4797bce5c11f04dcf0b478f43f0b1' 
  AND token = 'OF4YQC2LT0RSyUPcsy7pNr8BvvQ7OHIivuuHVV91y3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}