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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '844f2f0fbb12ae9b81bf41c46e21df21998b26d8813abd080fab04310f0f7c2c' 
  AND token = 'pS1Uwe9SMTuLotDL9igmOu+QvBy6/SIfc0guu5k7sVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}