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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa8367bdc40a05d84d25f843846383b26a999da32d758109992196bb6ac0cc94' 
  AND token = 'jzOvOJgnqd3gyTufqq8kDx2AQCPuH3gWl4//AF0fSY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}