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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9a99612e77a865c0db46e6dcd97d909b1cb036da91641e9d4cbdb12f39d5d77' 
  AND token = 'npzCE0N/DoMm290gKTfb4yQUtYt6A47AFFwxzf8OmDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}