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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9c2ed056a08f2c97d5bf089ee935c101399d21a4e0b281bc35e01b9734effb4' 
  AND token = 'cnHH+tYvgeXqvTyN0P4ko4EYavWnvkoI1HRDJCzQ/iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}