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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '908210a1e4c227e4fd148467f696524e51a99bda6d5096144c54f9189db0d50c' 
  AND token = 'zc5XSL9/LdsdohFDXAilOuT3UZC/N546GKNn2lDPRuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}