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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65fca28792f26d6103c64fb00cea65f3488ceab3664cf0f11f6de1d6c615dbbc' 
  AND token = 'sWUmNY+gF5UszHG+qR302QULbwlCu0EllA+C4cp/5v4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}