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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '742c27a74f826907b9c6a23500d1b38ca8953866b2cc0a205b7285f28bde56f0' 
  AND token = 'Y72r+SXb57uwVD5wGN8KZ2waCC2ZHGfKOVsdj1XKHQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}