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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d49d12e2546bbcb625ec2aff7b6a1f74fd61f8477ad3acd7aa747c6f704948d' 
  AND token = 'btyHfJ0FgKNWR+1MrXpz0N48GxTrUqwIWuL5ii5E6Mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}