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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f45a88a0751c86925ac9f025200242c7deee2d7b637d4a36ab6f0eed2a912e37' 
  AND token = '+O+JyZaCafRM6/eJmA8eBAtxD2lzGIDD7wK/YWxv+2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}