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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c02826a05a8fba024989f02b2e9d5182b3e13f79d0117e434694ed4f094f924' 
  AND token = 'UK8+jtOs4l3DpkVklG7OycU7DgXkoHlVOwr+XiudfFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}