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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3063da9c083dec1403389707d24e9fd0012cbab269c6bc7cb48b865c76fe529a' 
  AND token = 'CpbCCPvJRHcKIyj3OrD0vg5wO/RgLLpK1WXuRjpIxkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}