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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6fa9d351392aa9f8ba8cf8d026db8c0b958b0c603b3ab041f12d0d30893dd60' 
  AND token = 'wyX0pivYxW3ZANyQtLPSAd3HQ6wvQ0WEEfIvDT3rl84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}