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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b164bbc4806150991ef614e430ff8797d32f9e833624a6986cd7ace0978fe30' 
  AND token = 'MgZ5WYgPzqkLI6T5lXr38vSrOvANEICA0bGGIS6kbD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}