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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149b32c20c379ba98516e6da32d018832245673a2c1114aa1d0c2e717ad6e3c5' 
  AND token = 'KvLJcEgw1r8dgudQy4wtUOCYH8f5WRXqjjyPhOEB9yY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}