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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10757e6fdfe1d4e697ae69cd3d647e46c079134163c2c0c69539bd6916cca563' 
  AND token = 'G9jKAo+l8LHXmbs72hWBWx6lK/cGwJ3YoDBIzNo6Zp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}