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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d4726f1a2f67fc3210eb402ce628ce03e0d1978dc6db5b0430e6ed61d662476' 
  AND token = '6xfKHj84tTtg8zLCvNG0yN09rgwFAAzI8VibFHvtJ4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}