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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a14f870ae9840062c77fc26a6a9c651f0ce335671313c3142d5da431262f5313' 
  AND token = 'hDN7G3UWB37QfbCS/bqUEMHeU2gqkW/Om3iUjbX3CwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}