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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be2175a8cb51fe3f84a6a26f682ace3c8bcf872d4a087e53462ba76f9b32a810' 
  AND token = 'BrbLR2PdCwzmh06JlGx20mCmkOkb40H+IC9LNmLvFS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}