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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa0404dddf68a192e5293e047be74775b5f6121c54712dabb53e5b7b46e5b552' 
  AND token = '/PjTWLMwgumas/leReK5U3sNRy/l+YJtkCw85/cqkC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}