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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80f6502fb4fe1b387e942166987602292bc7ce4a98c8460a299dfa2dd4d47bb4' 
  AND token = '43hM4F28k6b3kIm7A5yT7nVxmDL2N175Z/dU625gTFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}