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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '546b44abc5b2ee12263e022265baf5508b9882c970db9f85e5a010250ec72fbd' 
  AND token = 'gIW8xyJkqlv116v2+a/z/EOnZ7yDdZyD/OTIN7cGGto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}