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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d6ac4801e99af39a9d5a22cb2629187d3713f008632cdb6d23ec9f180cfe015' 
  AND token = 'PXjSbU5Aw9RptAfmxwfXe8UCW5QGIwTniVnPl9xwBDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}