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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ea9beb0161cd4450de5daf5d89ac2591575b28c0c3b9f75e81bf22d48688db4' 
  AND token = 'g99vc/XlWq1DPnqtKfunxKSWEIveNIhJhdJnBKdjj8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}