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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e670d25f53f305d97301865f38a58f4f272ac61e7c9bfbdd4b7dc0e391b3bd0' 
  AND token = 'fEY6j+Yqxq+Bxy7kDjtk4LSlV0xFuDiuCSGQf9b9tWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}