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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab00b0dd0f19c0e1e8c5ce97d2a72803126e4d2886039f2bdf5c5b6a05a4fa15' 
  AND token = '4RM+PFarUrFOOuD2b0DggJBALJ5eU8QVZJsvhZl3D/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}