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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '549103f63b3f9675f33aa8acb8ac929b4bcffa898ccb4292c8de8292eb64c71a' 
  AND token = 'ZeCrLnQvSIUZlBIERxQcXN7Cy6ZMuI8z6pm0YYTCTu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}