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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ff89e16bc377e35dcaffe1e136bfe5686b8abb9977696d0993843d2c9b375be' 
  AND token = 'lFUrJeJtYtLvjma5HhrXmZ6I0oZljnJR9kJAIeU9U6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}