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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cce2703ee1ad6865585c12849c8e7e458b1fcba89b4f87349e9208187f4653b' 
  AND token = 'vGN8Yy4C+S3c9joMfbOnsa+SgXD5Y1XMoEkOD0ifMY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00266

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}