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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2f7d7c6d6add64d9a4bf32201155b4836e72743339102383b1e86a210198550' 
  AND token = 'vX9RtaHCsnS23+g2nBPJkX/rAJHuEHM1QT/FDmEcLSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}