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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '224237d179c0bfb410a2e3c7112e42bc1217f07dd567cf27cab8f77569618437' 
  AND token = 'jSlYraLxjJaVWGZtMuRFrwSBDSmW4o61QHXQ1G4HWFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}