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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aae6645ccaaea1a754d56aa7da61dabd36ca39414b37019f3c726f574b575ff0' 
  AND token = 'Gb+uOqtcp52/X+i5kH1jnJrLH4pH0up0iCvgEFA6qfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}