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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ef45d9b369009ff855c4c97d91a1b499f2491a5e17402696b2467fb0a5ede69' 
  AND token = 'rXhFJu7ztJMMdvtFnHWcKyhp3k7FtTESlC0E3rbDSXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}