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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '827264731d97c540c6f25b23e53d9927fe4098d0e4594cd581e8664ff6d87c26' 
  AND token = 'eTNxwxI7X3ZZ9jOlY1piWvCIL6oykk3BRNsPdUC7JqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}