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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e40a6aa5503bdecd8c1b685e8faff39a4f5fbe67908db09a05f060829abcfa0' 
  AND token = 'V8WXzDsXimQQPy5gAPWpyNhgy2uD0lWJ6QhZGsNWDNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}