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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c6246c6d51401b4534d16114bdc3fa4dd2fc058d9912aa238b31b670c4d64dc' 
  AND token = '5m74OVt6yE0rsKJKNaQYDCY0EF2Q0x84VKBKpJ6diZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}