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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e7aded0a0d21113a91f548585c38aba5008ed6d9a3015fe64a261c4d548771c' 
  AND token = '9ouflWeEKLaStQvfYryvQPvnRcMahjEUT19f6h9YfJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}