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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3423f9da5d2a5f4407a5255b485657694c5c0130bc6c3712c981c7e4030168a' 
  AND token = 'ygj6Woqe5y9mcwfxqaDms8zN/fvJIhRWymVd1UUPNAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}