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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4b52dd6807c805af55d24f9e252c1b765189dbd5aacc244a8e7206e0d37327a' 
  AND token = 'w1MSUbkERXzE61daRWLVV/us37qTOh+b7NmHBtU1ya0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}