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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10ded59c72f5804a71860657ac00ad4fe478832a532c66c61efdc2ff0a88a754' 
  AND token = '+alPSGMYRCgegLlEItXdMDNI0YSFXxGDq78ohF+gmBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}